Description

L-Isovaline, 4-Amino-4-Oxo-, Methyl Ester (9Ci) is a high-purity, non-proteinogenic amino acid derivative with a defined chiral center. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, peptide mimetics, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Peptidomimetics Research: Used to incorporate non-standard amino acid structures into peptide chains to enhance stability, bioavailability, and biological activity.
• Medicinal Chemistry: Serves as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in studies of amino acid metabolism, neurotransmission, and as a tool compound in biological assays.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Development: Potential intermediate in the synthesis of novel, chiral herbicides or plant growth regulators.

Basic Information

Product Name	L-Isovaline, 4-Amino-4-Oxo-, Methyl Ester (9Ci)
CAS No.	693771-70-9
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	L-2-Amino-2-methylbutanoic acid 4-methyl ester; Methyl L-isovaline-4-carboxylate; (2S)-2-Amino-2-methylbutanoic acid methyl ester; L-Isovaline methyl ester; 4-Amino-4-oxo-L-isovaline methyl ester; 693771-70-9; Methyl (2S)-2-amino-2-methylbutanoate
EINECS	Contact for details

Quality Control

Our L-Isovaline, 4-Amino-4-Oxo-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (L-Isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.