Description

Benzenemethanol, 2,3-Difluoro-α-Methyl-, (Alphas)- (9Ci) is a high-purity fluorinated benzyl alcohol derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in the precise stereochemistry and the introduction of fluorine atoms, which are essential for modulating the biological activity and metabolic stability of target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in creating advanced, high-efficacy pesticides and herbicides where the fluorine atoms enhance lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic semiconductors.
• Asymmetric Catalysis Ligand Precursor: The chiral backbone can be utilized to develop novel ligands for asymmetric hydrogenation and cross-coupling reactions.
• Advanced Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or specific optical properties.
• Diagnostic Reagent Development: Employed in synthesizing fluorinated probes and tags for biomedical imaging and assay development.

Basic Information

Item	Details
Product Name	Benzenemethanol, 2,3-Difluoro-α-Methyl-, (Alphas)- (9Ci)
CAS No.	691881-96-6
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(αS)-2,3-Difluoro-α-methylbenzenemethanol; (S)-1-(2,3-Difluorophenyl)ethanol; (S)-α-Methyl-2,3-difluorobenzyl alcohol; 2,3-Difluoro-α-methylbenzyl alcohol (S)-; (S)-2,3-Difluoro-α-methylbenzyl alcohol; (S)-1-(2,3-Difluorophenyl)ethan-1-ol; (αS)-α-Methyl-2,3-difluorobenzenemethanol
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, 2,3-Difluoro-α-Methyl-, (Alphas)- (9Ci) adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.