Description

Ethanone, 2,2,2-Trifluoro-1-Imidazo[1,2-A]Pyrimidin-3-Yl- (9Ci) CAS NO 691372-19-7 is a specialized trifluoroacetylated heterocyclic compound, serving as a high-value synthetic intermediate. Its core value lies in enabling the introduction of the trifluoroacetyl group into complex molecular architectures, a key modification for tuning the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and environmental stability.
• Material Science Precursor: Serves as a precursor for synthesizing specialty chemicals and functional materials, including ligands for catalysis and monomers for advanced polymers.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Academic & Contract Research: A critical reagent for methodological development in organic synthesis and heterocyclic chemistry within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-Imidazo[1,2-A]Pyrimidin-3-Yl- (9Ci)
CAS No.	691372-19-7
Molecular Formula	C8H4F3N3O
Molecular Weight	215.13 g/mol
Synonyms	2,2,2-Trifluoro-1-(imidazo[1,2-a]pyrimidin-3-yl)ethanone; 1-(Imidazo[1,2-a]pyrimidin-3-yl)-2,2,2-trifluoroethanone; 3-Trifluoroacetyl-imidazo[1,2-a]pyrimidine; Trifluoroacetyl Imidazopyrimidine; CAS 691372-19-7
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2,2,2-Trifluoro-1-Imidazo[1,2-A]Pyrimidin-3-Yl- (9Ci) adheres to a strict quality management system. Every batch is subjected to comprehensive analytical characterization, including NMR, HPLC, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.