Description

2-Oxo-4-(4-Pyridinyl)-1,2-Dihydro-5-Pyrimidinecarboxylic Acid Hydrate is a high-purity heterocyclic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique pyrimidine-pyridine fused structure makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production in pharmaceutical development, agrochemical synthesis, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and plant growth regulators with specific modes of action.
• Chemical Synthesis Building Block: Employed in organic synthesis to construct complex heterocyclic frameworks for material science and catalysis.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and biochemical pathway analysis.
• Material Science: A potential monomer or additive for creating specialty polymers with tailored electronic or optical properties.
• Academic & Industrial R&D: Used in discovery chemistry for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2-Oxo-4-(4-Pyridinyl)-1,2-Dihydro-5-Pyrimidinecarboxylic Acid Hydrate
CAS No.	690631-95-9
Molecular Formula	C10H7N3O3 · xH2O
Molecular Weight	217.18 g/mol (Anhydrous basis)
Synonyms	5-Pyrimidinecarboxylic acid, 1,2-dihydro-2-oxo-4-(4-pyridinyl)-, hydrate; 4-(4-Pyridyl)-2-oxo-1,2-dihydro-5-pyrimidinecarboxylic acid hydrate; 2-Hydroxy-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid hydrate; 4-(4-Pyridinyl)-2-oxo-1,2-dihydro-5-pyrimidinecarboxylic acid monohydrate; 2-Oxo-4-(4-pyridyl)-1,2-dihydropyrimidine-5-carboxylic acid hydrate
EINECS	Contact for details

Quality Control

Our 2-Oxo-4-(4-Pyridinyl)-1,2-Dihydro-5-Pyrimidinecarboxylic Acid Hydrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and KF titration for water content. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.