Description

3-Buten-2-One, 4-(2-Pyrimidinyl)-, (3E)- (9Ci) is a specialized organic building block featuring a conjugated enone system linked to a pyrimidine heterocycle, making it a valuable scaffold for advanced chemical synthesis. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and functional materials where precise molecular architecture is required. Its primary utility lies in serving as a key intermediate in medicinal chemistry, particularly for the construction of complex molecules targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially those with pyrimidine-based core structures for oncology, antiviral, or CNS applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive α,β-unsaturated ketone moiety for creating bioactive molecules.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probe Synthesis: Employed to create molecular probes and labeled compounds for studying biological pathways and enzyme functions.
• Academic & Industrial R&D: A versatile reagent for methodology development in organic synthesis, including cycloaddition and conjugate addition reactions.

Basic Information

Product Name	3-Buten-2-One, 4-(2-Pyrimidinyl)-, (3E)- (9Ci)
CAS No.	688800-76-2
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	(3E)-4-(Pyrimidin-2-yl)but-3-en-2-one; 4-(2-Pyrimidinyl)-3-buten-2-one, (E)-; 2-Pyrimidinyl 3-buten-2-one; (E)-1-(Pyrimidin-2-yl)but-2-en-1-one; (E)-4-(Pyrimidin-2-yl)but-3-en-2-one; 688800-76-2; (3E)-4-(2-Pyrimidinyl)-3-buten-2-one
EINECS	Contact for details

Quality Control

Every batch of 3-Buten-2-One, 4-(2-Pyrimidinyl)-, (3E)- (9Ci) is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.