Description

4-(2-Amino-6-Chloropyrimidin-4-Yl)Butanoic Acid is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino-chloropyrimidine core and a butanoic acid side chain, makes it an invaluable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent synthesis.
• Agrochemical Research: Used as a precursor in the design and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity tags for studying enzyme function and protein interactions.
• Material Science: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	4-(2-Amino-6-Chloropyrimidin-4-Yl)Butanoic Acid
CAS No.	688782-59-4
Molecular Formula	C8H10ClN3O2
Molecular Weight	215.64 g/mol
Synonyms	4-(2-Amino-6-chloro-4-pyrimidinyl)butanoic acid; 2-Amino-6-chloro-4-(3-carboxypropyl)pyrimidine; Butanoic acid, 4-(2-amino-6-chloro-4-pyrimidinyl)-; 4-(2-Amino-6-chloropyrimidin-4-yl)butyric acid; 2-Amino-6-chloro-4-(4-carboxybutyl)pyrimidine (common misnomer); 4-(2-Amino-6-chloro-pyrimidin-4-yl)-butyric acid; 688782-59-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 4-(2-Amino-6-Chloropyrimidin-4-Yl)Butanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development under quality systems suitable for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.