Description

4-(2-Methoxyphenyl)-2-[4-(2-Methoxyphenyl)Piperazin-1-Yl]-6-(Trifluoromethyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop new therapeutic candidates with enhanced efficacy and selectivity.

Application

• Key intermediate in the research and development of novel pharmaceutical compounds, especially for CNS applications.
• Building block for the synthesis of potent and selective receptor ligands in medicinal chemistry.
• Used in preclinical and process chemistry for scale-up studies and route optimization.
• Critical material in academic and industrial research focusing on piperazine and pyrimidine-based drug discovery.
• Employed in the development of targeted therapies requiring specific molecular architectures.

Basic Information

Product Name	4-(2-Methoxyphenyl)-2-[4-(2-Methoxyphenyl)Piperazin-1-Yl]-6-(Trifluoromethyl)Pyrimidine
CAS No.	686725-20-2
Molecular Formula	C24H24F3N5O2
Molecular Weight	471.48 g/mol
Synonyms	2-[4-(2-Methoxyphenyl)piperazin-1-yl]-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidine; 4-(2-Methoxyphenyl)-2-[4-(2-methoxyphenyl)-1-piperazinyl]-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-2,4-bis(2-methoxyphenyl)piperazinylpyrimidine; 686725-20-2; UNII-9V7A8UQ81N; 9V7A8UQ81N; 4-(2-Methoxyphenyl)-2-(4-(2-methoxyphenyl)piperazin-1-yl)-6-(trifluoromethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-(2-Methoxyphenyl)-2-[4-(2-Methoxyphenyl)Piperazin-1-Yl]-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing full specifications and confirming compliance with customer and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.