Description

4-Amino-1-[2,3-o-(1-methylethylidene)pentofuranosyl]-1,3,5-triazin-2(1H)-one is a specialized nucleoside analog with significant potential in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of modified nucleosides and nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies investigating enzyme inhibition, nucleic acid metabolism, and mechanism of action.
• Antiviral Drug Development: Serves as a precursor in the research and development of potential therapeutics targeting viral polymerases.
• Oncology Research: Investigated for incorporation into prodrugs or targeted therapies designed to disrupt cancer cell DNA/RNA synthesis.
• Nucleoside Chemistry: A valuable reagent for academic and industrial research focused on modifying sugar and base moieties of nucleosides.
• Preclinical Studies: Utilized in the early-stage development and screening of new chemical entities (NCEs) for biological activity.

Basic Information

Product Name	4-Amino-1-[2,3-o-(1-methylethylidene)pentofuranosyl]-1,3,5-triazin-2(1H)-one
CAS No.	686300-58-3
Molecular Formula	C11H16N4O5
Molecular Weight	284.27 g/mol
Synonyms	4-Amino-1-(2,3-O-isopropylidene-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 4-Amino-1-(2,3-O-isopropylidene-β-D-ribofuranosyl)-as-triazin-2-one; 1-(2,3-Di-O-isopropylidene-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one; Isopropylidene-protected ribofuranosyl triazinone nucleoside; 4-Amino-1-(2,3-O-isopropylidene-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 4-Amino-1-[2,3-o-(1-methylethylidene)pentofuranosyl]-1,3,5-triazin-2(1H)-one is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.