Description

4-{[4-(2-Thienyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Sulfonyl}Butanoic Acid is a high-value, multifunctional organic intermediate featuring a pyrimidine core substituted with thienyl and trifluoromethyl groups, linked via a sulfonyl bridge to a butanoic acid chain. This compound is critical for its role in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts desirable electronic and physicochemical properties. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the bioactivity of the pyrimidine-thiophene scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as semiconductors and light-emitting components.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and signaling pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	4-{[4-(2-Thienyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Sulfonyl}Butanoic Acid
CAS No.	685837-06-3
Molecular Formula	C13H11F3N2O4S2
Molecular Weight	380.36 g/mol
Synonyms	4-[(4-Thiophen-2-yl-6-(trifluoromethyl)pyrimidin-2-yl)sulfonyl]butanoic acid; Butanoic acid, 4-[[4-(2-thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]-; 4-({4-[Thiophen-2-yl]-6-(trifluoromethyl)pyrimidin-2-yl}sulfonyl)butyric acid; 685837-06-3; 4-[[4-(2-Thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]butanoic acid
EINECS	Contact for details

Quality Control

Our production of 4-{[4-(2-Thienyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Sulfonyl}Butanoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Our quality system is designed to guarantee batch-to-batch consistency and supply reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.