Description

6-(Methylsulfonyl)-3-(Phenylsulfonyl)Pyrazolo[1,5-A]Pyrimidin-7-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazolo[1,5-a]pyrimidine core. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel small-molecule drug candidates.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and optimization of potent kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic value.
• Process Chemistry & Scale-Up: Employed in route scouting and process optimization for the commercial-scale manufacturing of target APIs.
• Contract Research & Development (CRO/CDMO): Supplied to organizations specializing in custom synthesis and early-stage drug development services.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control.

Basic Information

Item	Details
Product Name	6-(Methylsulfonyl)-3-(Phenylsulfonyl)Pyrazolo[1,5-A]Pyrimidin-7-Amine
CAS No.	685107-43-1
Molecular Formula	C₁₃H₁₂N₄O₄S₂
Molecular Weight	352.39 g/mol
Synonyms	6-(Methylsulfonyl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-amine; 7-Amino-6-(methylsulfonyl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine; 685107-43-1; Pyrazolo[1,5-a]pyrimidin-7-amine, 6-(methylsulfonyl)-3-(phenylsulfonyl)-; 6-Methanesulfonyl-3-(benzenesulfonyl)pyrazolo[1,5-a]pyrimidin-7-amine
EINECS	Contact for details

Quality Control

Our 6-(Methylsulfonyl)-3-(Phenylsulfonyl)Pyrazolo[1,5-A]Pyrimidin-7-Amine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.