Description

1-(4-[2-(2-Pyridinyl)-4-Pyrimidinyl]Phenyl)-1H-1,3-Benzimidazole is a high-purity, heterocyclic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical building block or intermediate in the synthesis of novel therapeutic agents, particularly those targeting specific enzymatic pathways. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery programs. The compound's unique fused ring structure makes it a valuable scaffold for developing potent and selective bioactive molecules.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of new chemical entities (NCEs) for oncology, antiviral, and other therapeutic areas.
• Kinase Inhibitor Research: Core scaffold for the design and synthesis of potential protein kinase inhibitors due to its benzimidazole and pyrimidine motifs.
• Biochemical Tool Compound: Used in high-throughput screening (HTS) and in vitro assays to study biological pathways and identify drug targets.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct more elaborate molecular architectures.
• Material Science Research: Potential precursor for the development of organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Development (CRO): Supplied to CROs and CDMOs supporting external drug discovery pipelines.

Basic Information

Product Name	1-(4-[2-(2-Pyridinyl)-4-Pyrimidinyl]Phenyl)-1H-1,3-Benzimidazole
CAS No.	685106-90-5
Molecular Formula	C22H15N5
Molecular Weight	349.39 g/mol
Synonyms	1-(4-(2-(Pyridin-2-yl)pyrimidin-4-yl)phenyl)-1H-benzimidazole; 1-[4-[2-(2-Pyridinyl)-4-pyrimidinyl]phenyl]-1H-benzimidazole; UNII-9V2I8T2J8M; 9V2I8T2J8M; Benzimidazole, 1-[4-[2-(2-pyridinyl)-4-pyrimidinyl]phenyl]-; 1-(4-(2-(pyridin-2-yl)pyrimidin-4-yl)phenyl)-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our 1-(4-[2-(2-Pyridinyl)-4-Pyrimidinyl]Phenyl)-1H-1,3-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.