Description

3-(2,4-Dichlorophenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block in the pharmaceutical industry, primarily used in solid-phase peptide synthesis (SPPS) as an Fmoc-protected intermediate. It is essential for research chemists and process development teams creating novel peptide-based therapeutics, diagnostics, and biochemical tools. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency and synthesis integrity.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid building block for the automated synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for peptide hormones, antibiotics, and targeted drug conjugates.
• Bioconjugation & Probe Development: Facilitates the site-specific incorporation of functional groups or labels into peptides for diagnostic assays and imaging agents.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds and lead optimization.
• Academic & Industrial R&D: A fundamental reagent for investigating peptide structure-activity relationships (SAR) and developing novel synthetic methodologies.
• Custom Peptide Service Providers: A critical raw material for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Item	Detail
Product Name	3-(2,4-Dichlorophenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid
CAS No.	683217-93-8
Molecular Formula	C24H19Cl2NO4
Molecular Weight	456.32 g/mol
Synonyms	Fmoc-3-(2,4-Dichlorophenyl)-β-alanine; Fmoc-3-(2,4-Dichlorophenyl)-β-homoalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2,4-dichlorophenyl)-β-alanine; N-Fmoc-3-(2,4-dichlorophenyl)-β-alanine; 3-(2,4-Dichlorophenyl)-3-[(9-fluorenylmethoxycarbonyl)amino]propanoic acid; Fmoc-Dcp-OH; Fmoc-3-(2,4-DCP)-Ala-OH; Fmoc-β-(2,4-Dichlorophenyl)-Ala-OH
EINECS	Contact for details

Quality Control

Every batch of 3-(2,4-Dichlorophenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid is manufactured under strict quality management systems. We perform comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and conformity to the highest standards for peptide synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light may affect purity and performance. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.