Description

(±)-3-(Fmoc-Amino)-2-Phenylpropionic Acid is a protected amino acid derivative widely used as a key building block in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled introduction of phenylalanine analogs into peptide chains, enabling the research and development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on peptide-based drug discovery, diagnostics, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the automated synthesis of custom peptides.
• Pharmaceutical Research: Building block for creating peptide libraries and novel drug candidates targeting various diseases.
• Bioconjugation: Used to introduce functional handles or labels onto peptides and proteins for diagnostic or therapeutic purposes.
• Chemical Biology Probes: Synthesis of labeled or modified peptides used to study protein-protein interactions and enzyme function.
• Antibody-Drug Conjugate (ADC) Development: Potential use in constructing specialized linkers or payloads for targeted cancer therapies.
• Academic & Institutional Research: A critical reagent for graduate-level and post-doctoral research in synthetic organic chemistry and peptide science.

Basic Information

Product Name	(±)-3-(Fmoc-Amino)-2-Phenylpropionic Acid
CAS No.	683217-60-9
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-3-Amino-2-phenylpropionic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-2-phenylpropanoic acid; DL-3-(Fmoc-Amino)-2-phenylpropionic acid; 2-Phenyl-3-[(9H-fluoren-9-ylmethoxycarbonyl)amino]propanoic acid; Fmoc-DL-3-Amino-2-phenylpropionic acid; N-Fmoc-3-amino-2-phenylpropionic acid; 3-(Fmoc-amino)-2-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our (±)-3-(Fmoc-Amino)-2-Phenylpropionic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is analyzed via HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.