Description

Ethyl 1-(1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)Piperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potent kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used as a scaffold or building block in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Oncology Drug Development: Employed in the research and development of targeted cancer therapies due to its pyrazolopyrimidine core, a common pharmacophore in kinase inhibition.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for biochemical studies and the exploration of new therapeutic pathways.
• Process Chemistry: Applied in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Ethyl 1-(1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)Piperidine-4-Carboxylate
CAS No.	681428-42-2
Molecular Formula	C15H19N5O2
Molecular Weight	301.35 g/mol
Synonyms	Ethyl 4-[(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]piperidine-1-carboxylate; 1-Methyl-4-(piperidin-4-yloxy)-1H-pyrazolo[3,4-d]pyrimidine ethyl carboxylate; 681428-42-2; UNII-9I17114E6F; 4-[(1-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]piperidine-1-carboxylic Acid Ethyl Ester; 9I17114E6F; Ethyl 1-[(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of Ethyl 1-(1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)Piperidine-4-Carboxylate adheres to stringent quality systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.