Description

5,7-Difluoro-3-Indolecarboxylic Acid Methyl Ester is a high-value fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced activity and selectivity.
• Organic Synthesis: Serves as a versatile precursor for constructing complex indole-based heterocycles and fine chemicals.
• Material Science: Potential monomer or additive in the development of specialty polymers and advanced organic electronic materials.
• Biochemical Probes: Utilized in the creation of fluorescent tags and molecular probes for biological imaging and assay development.

Basic Information

Product Name	5,7-Difluoro-3-Indolecarboxylic Acid Methyl Ester
CAS No.	681288-42-6
Molecular Formula	C10H7F2NO2
Molecular Weight	211.16 g/mol
Synonyms	Methyl 5,7-Difluoro-1H-indole-3-carboxylate; 5,7-Difluoroindole-3-carboxylic Acid Methyl Ester; 3-Carbomethoxy-5,7-difluoroindole; 1H-Indole-3-carboxylic acid, 5,7-difluoro-, methyl ester; Methyl 5,7-difluoro-1H-indole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-3-Indolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to minimize potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.