Description

6-(Chloromethyl)-2-(3-Methylphenyl)Pyrimidin-4-Ol is a high-purity pyrimidine derivative, a key chemical building block prized for its reactive chloromethyl group and aromatic substitution pattern. This compound matters for its role as a versatile synthetic intermediate in the development of more complex, high-value molecules. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic core.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	6-(Chloromethyl)-2-(3-Methylphenyl)Pyrimidin-4-Ol
CAS No.	680214-71-5
Molecular Formula	C12H11ClN2O
Molecular Weight	234.68 g/mol
Synonyms	2-(3-Methylphenyl)-6-(chloromethyl)-4-pyrimidinol; 6-(Chloromethyl)-2-(m-tolyl)pyrimidin-4-ol; 4-Pyrimidinol, 6-(chloromethyl)-2-(3-methylphenyl)-; 2-(3-Methylphenyl)-6-chloromethylpyrimidin-4-ol; 6-Chloromethyl-2-(3-methylphenyl)pyrimidin-4-ol; 680214-71-5; 2-(m-Tolyl)-6-(chloromethyl)pyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our 6-(Chloromethyl)-2-(3-Methylphenyl)Pyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chloromethyl group, it should be stored separately from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.