Description

Ethyl 7-(4-Methylphenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of investigational drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for developing potent and selective inhibitors for oncology and inflammatory disease research.
• Chemical Biology & Proteomics: Used as a tool compound or a tagged ligand for studying enzyme function and protein-ligand interactions.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents due to its heterocyclic structure.
• Material Science Exploration: Investigated for creating novel organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	Ethyl 7-(4-Methylphenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	678983-41-0
Molecular Formula	C16H15N3O2
Molecular Weight	281.31 g/mol
Synonyms	Ethyl 7-(p-Tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 7-(4-Methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid Ethyl Ester; Ethyl 7-(4-Methylphenyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylate; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-(4-methylphenyl)-, ethyl ester; 678983-41-0; Ethyl 7-(4-Methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 7-(4-Methylphenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.