Description

5-(4-Ethyl-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex pyrazolo[1,5-a]pyrimidine derivatives for material science and specialty chemical applications.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• API Development: Integral in the process development and scale-up stages for new Active Pharmaceutical Ingredients (APIs) requiring this specific trifluoromethyl-substituted heterocycle.

Basic Information

Product Name	5-(4-Ethyl-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	678543-10-7
Molecular Formula	C16H12F3N3O2
Molecular Weight	335.28 g/mol
Synonyms	5-(4-Ethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 7-Trifluoromethyl-5-(4-ethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 678543-10-7; 5-(p-Ethylphenyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(4-Ethyl-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.