Description

4-Ethoxy-3-[(Morpholine-4-Carbonyl)-Amino]-Benzenesulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, serving as a versatile electrophile for sulfonamide formation and a protected intermediate for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition via sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides where the benzenesulfonyl chloride moiety is integral to biological activity.
• Chemical Research & Development: A valuable reagent for medicinal chemists exploring structure-activity relationships (SAR) and creating targeted compound libraries.
• Fine Chemical Production: Serves as a specialized building block for synthesizing complex, high-value molecules used in material science and specialty chemistry.
• Protease Inhibitor Scaffolds: Potential use in constructing molecular scaffolds for protease inhibitors, leveraging the sulfonyl chloride's reactivity with amines.

Basic Information

Product Name	4-Ethoxy-3-[(Morpholine-4-Carbonyl)-Amino]-Benzenesulfonyl Chloride
CAS No.	678186-07-7
Molecular Formula	C13H17ClN2O5S
Molecular Weight	348.80 g/mol
Synonyms	4-Ethoxy-3-[(morpholine-4-carbonyl)amino]benzenesulfonyl chloride; 3-[(Morpholine-4-carbonyl)amino]-4-ethoxybenzenesulfonyl chloride; N-(4-Ethoxy-3-sulfamoylphenyl)morpholine-4-carboxamide chloride; 4-Ethoxy-3-(morpholine-4-carboxamido)benzenesulfonyl chloride; 678186-07-7; Benzenesulfonyl chloride, 4-ethoxy-3-[(4-morpholinylcarbonyl)amino]-
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-[(Morpholine-4-Carbonyl)-Amino]-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.