Description

4-Ethoxy-3-[3-(3-Nitro-Phenyl)-Ureido]-Benzene-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a key electrophilic intermediate, enabling the introduction of the sulfonamide functional group into complex molecular architectures. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides where the sulfonamide moiety is essential for bioactivity.
• Dye and Pigment Manufacturing: Serves as a reactive intermediate for creating sulfonated azo dyes and other colorants with enhanced properties.
• Material Science Research: Employed in the synthesis of functional polymers and advanced materials requiring sulfonamide linkages.
• Chemical Biology Probes: Utilized for labeling proteins or modifying biomolecules due to its reactive sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	4-Ethoxy-3-[3-(3-Nitro-Phenyl)-Ureido]-Benzene-Sulfonyl Chloride
CAS No.	678185-98-3
Molecular Formula	C15H14ClN3O6S
Molecular Weight	423.81 g/mol
Synonyms	4-Ethoxy-3-[3-(3-nitrophenyl)ureido]benzenesulfonyl chloride; 3-[(3-Ethoxy-4-sulfamoylphenyl)carbamoyl]aminonitrobenzene (related); N-(3-Ethoxy-4-sulfonylchloridophenyl)-N'-(3-nitrophenyl)urea; 678185-98-3; 4-Ethoxy-3-[[(3-nitrophenyl)amino]carbonyl]amino]benzenesulfonyl chloride; 3-Nitro-N-[[3-ethoxy-4-(chlorosulfonyl)phenyl]carbamoyl]aniline
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-[3-(3-Nitro-Phenyl)-Ureido]-Benzene-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.