Description

3-Chloro-4-(3-Methyl-Ureido)-Benzenesulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative essential for advanced organic synthesis. This compound serves as a critical building block for introducing the sulfonamide pharmacophore, enabling the development of novel active molecules. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with sulfonamide moieties.
• Chemical Research: A versatile reagent for constructing complex molecular architectures in medicinal chemistry and material science projects.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3-Chloro-4-(3-Methyl-Ureido)-Benzenesulfonyl Chloride
CAS No.	678185-87-0
Molecular Formula	C8H8Cl2N2O3S
Molecular Weight	283.13 g/mol
Synonyms	1-(4-Chloro-3-sulfamoylphenyl)-3-methylurea; 3-Chloro-4-[(methylcarbamoyl)amino]benzenesulfonyl chloride; 4-Chloro-3-[(methylamino)carbonyl]aminobenzenesulfonyl chloride; N-(4-Chloro-3-sulfonylchloridophenyl)-N'-methylurea; 678185-87-0; Benzenesulfonyl chloride, 3-chloro-4-[(methylamino)carbonyl]amino]-; 3-Chloro-4-(3-methylureido)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(3-Methyl-Ureido)-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.