Description

2-Methyl-4-[(Morpholine-4-Carbonyl)Amino]Benzenesulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative designed for advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile handle for sulfonamide bond formation. It is primarily utilized by research and development teams, process chemists, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific sulfonamide functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition via sulfonamide groups.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides with tailored activity profiles.
• Chemical Biology & Proteomics: Serves as a reactive probe or linker for modifying proteins, peptides, and other biomolecules to study function or create conjugates.
• Material Science Research: Employed in the development of specialty polymers, dyes, and functional materials where the sulfonyl chloride group enables covalent attachment.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.

Basic Information

Product Name	2-Methyl-4-[(Morpholine-4-Carbonyl)Amino]Benzenesulfonyl Chloride
CAS No.	678185-66-5
Molecular Formula	C13H15ClN2O4S
Molecular Weight	330.79 g/mol
Synonyms	4-Amino-2-methylbenzenesulfonyl chloride, N-(morpholine-4-carbonyl) derivative; 2-Methyl-4-(morpholine-4-carboxamido)benzenesulfonyl chloride; 4-(Morpholine-4-carbonyl)amino-2-methylbenzenesulfonyl chloride; N-(4-Chlorosulfonyl-3-methylphenyl)morpholine-4-carboxamide; CAS 678185-66-5; Morpholine-4-carboxylic acid [4-(chlorosulfonyl)-3-methylphenyl]amide
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-[(Morpholine-4-Carbonyl)Amino]Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP (current Good Manufacturing Practice) for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.