Description

Ethyl 2-Morpholino-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is a high-value, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a morpholine ring and a trifluoromethyl group, makes it an essential intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Chemical Synthesis Building Block: Employed in organic chemistry for constructing complex heterocyclic compounds and functional materials.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique properties.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for exploratory chemistry and method development.

Basic Information

Product Name	Ethyl 2-Morpholino-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate
CAS No.	677706-89-7
Molecular Formula	C12H14F3N3O3
Molecular Weight	305.25 g/mol
Synonyms	Ethyl 2-morpholino-4-(trifluoromethyl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-morpholino-4-(trifluoromethyl)-, ethyl ester; 2-Morpholino-4-(trifluoromethyl)pyrimidine-5-carboxylic acid ethyl ester; Ethyl 2-(morpholin-4-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate; CAS 677706-89-7
EINECS	Contact for details

Quality Control

Our Ethyl 2-Morpholino-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity requirements, our technical team is available to discuss tailored quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.