Description

Ent-Pazufloxacin Mesylate is the mesylate salt form of the enantiomer of pazufloxacin, a synthetic fluoroquinolone antibiotic. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis and study of novel antibacterial agents. It is essential for manufacturers and research institutions focused on developing enantiomerically pure active pharmaceutical ingredients (APIs) to combat resistant bacterial strains.

Application

• Primary use as a key chiral intermediate in the synthesis of enantiomerically pure fluoroquinolone antibiotics.
• Research and development of novel antibacterial agents targeting drug-resistant pathogens.
• Preclinical and clinical studies to investigate the pharmacokinetics and efficacy of specific enantiomers.
• Production of reference standards for analytical method development and quality control in pharmaceutical manufacturing.
• Chemical synthesis for exploring structure-activity relationships (SAR) within the fluoroquinolone class.
• Development of specialized pharmaceutical formulations requiring high enantiomeric purity.

Basic Information

Product Name	Ent-Pazufloxacin Mesylate
CAS No.	677004-96-5
Molecular Formula	C16H15FN2O4 • CH4O3S
Molecular Weight	398.37 g/mol
Synonyms	(-)-Pazufloxacin Mesylate; (S)-Pazufloxacin Mesylate; Pazufloxacin Impurity; (S)-10-(1-Aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid methanesulfonate; UNII-1J8L7R6K8P; Pazufloxacin Mesylate Enantiomer; Ent-Pazufloxacin Methanesulfonate
EINECS	Contact for details

Quality Control

Our Ent-Pazufloxacin Mesylate is manufactured under strict quality systems to ensure high chemical and enantiomeric purity suitable for pharmaceutical research. Each batch is analyzed using advanced chromatographic techniques, including chiral HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, impurity profile, and residual solvents is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.