Description

Ethyl 5-(1-Adamantyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate is a high-value, synthetically advanced heterocyclic compound featuring a unique adamantyl-trifluoromethyl-pyrazolopyrimidine core structure. This compound is of significant interest for its potential as a key pharmaceutical intermediate or biological probe in medicinal chemistry research and development. It is primarily sought by R&D teams and process chemists in the pharmaceutical, agrochemical, and advanced material sectors for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive molecules.
• Agrochemical Development: Potential application as an intermediate in the synthesis of new-generation pesticides or herbicides, leveraging its complex heterocyclic structure.
• Chemical Biology Tool: Can be utilized as a probe or ligand in biochemical assays to study protein-ligand interactions and enzyme inhibition.
• Advanced Material Precursor: May find use in the development of specialty polymers or organic electronic materials due to its rigid adamantyl group and fluorinated moiety.

Basic Information

Product Name	Ethyl 5-(1-Adamantyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	676589-12-1
Molecular Formula	C20H22F3N3O2
Molecular Weight	393.40 g/mol
Synonyms	Ethyl 5-(1-adamantyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 5-Adamantan-1-yl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Ethyl 5-tricyclo[3.3.1.1³,⁷]dec-1-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; CAS 676589-12-1; Adamantyl-trifluoromethyl-pyrazolopyrimidine carboxylate; 7-Trifluoromethyl-5-adamantyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(1-Adamantyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.