Description

2-Mercapto-3-(3,4,5-Trimethoxyphenyl)Quinazolin-4(3H)-One is a specialized quinazolinone derivative, a high-value chemical intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a quinazolinone core with a trimethoxyphenyl group and a thiol functionality, making it a versatile precursor for pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the development of novel therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Biology & Proteomics: The thiol (mercapto) group can be utilized for bioconjugation, labeling, or as a handle for creating chemical probes to study biological systems.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Mercapto-3-(3,4,5-Trimethoxyphenyl)Quinazolin-4(3H)-One
CAS No.	676588-99-1
Molecular Formula	C17H16N2O4S
Molecular Weight	344.39 g/mol
Synonyms	2-Mercapto-3-(3,4,5-trimethoxyphenyl)-4(3H)-quinazolinone; 3-(3,4,5-Trimethoxyphenyl)-2-mercapto-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-mercapto-3-(3,4,5-trimethoxyphenyl)-; 2-Thiol-3-(3,4,5-trimethoxyphenyl)quinazolin-4-one; 2-Sulfanyl-3-(3,4,5-trimethoxyphenyl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our production of 2-Mercapto-3-(3,4,5-Trimethoxyphenyl)Quinazolin-4(3H)-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.