Description

2-Naphthalenol, 1,7,8-Trifluoro- is a specialized fluorinated naphthol derivative, a high-value intermediate prized for its unique electronic and steric properties imparted by the fluorine substituents. This compound is critical for applications requiring precise molecular tuning, such as in the development of advanced materials and active pharmaceutical ingredients. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical sectors for synthesis and process optimization.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter physical properties such as refractive index, chemical resistance, and thermal performance.
• Dye & Pigment Intermediate: Utilized in the synthesis of high-performance, light-fast dyes and pigments for industrial applications.
• Research & Development: A valuable tool compound in academic and industrial laboratories for studying fluorination effects and developing new synthetic methodologies.

Basic Information

Product Name	2-Naphthalenol, 1,7,8-Trifluoro-
CAS No.	676545-61-2
Molecular Formula	C₁₀H₅F₃O
Molecular Weight	198.14 g/mol
Synonyms	1,7,8-Trifluoro-2-naphthol; 1,7,8-Trifluoro-2-naphthalenol; 2-Hydroxy-1,7,8-trifluoronaphthalene; 1,7,8-Trifluoronaphthalen-2-ol; 2-Naphthol, 1,7,8-trifluoro-; 1,7,8-Trifluoro-2-hydroxynaphthalene
EINECS	Contact for details

Quality Control

Every batch of 2-Naphthalenol, 1,7,8-Trifluoro- is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality commitment supports compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.