Description

Benzaldehyde, 2,3,5-Trifluoro-4-Hydroxy- is a high-value fluorinated aromatic aldehyde building block, distinguished by its unique trifluoro and hydroxy substitution pattern. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where its specific fluorine substitution can dramatically alter biological activity, metabolic stability, and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atoms enhance product efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced thermal and chemical resistance.
• Complex Ligand Synthesis: Utilized in organometallic chemistry and catalysis to create sophisticated ligands for asymmetric synthesis.
• Research & Development: A valuable tool for medicinal chemistry and chemical biology research in academic and industrial laboratories.

Basic Information

Product Name	Benzaldehyde, 2,3,5-Trifluoro-4-Hydroxy-
CAS No.	676500-50-8
Molecular Formula	C7H3F3O2
Molecular Weight	176.09 g/mol
Synonyms	2,3,5-Trifluoro-4-hydroxybenzaldehyde; 4-Hydroxy-2,3,5-trifluorobenzaldehyde; 2,3,5-Trifluoro-4-hydroxybenzenecarboxaldehyde; 2,3,5-Trifluoro-4-hydroxy-benzaldehyde; 4-Formyl-2,3,5-trifluorophenol
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 2,3,5-Trifluoro-4-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.