Description

5-(4-Ethyl-Phenyl)-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 676459-69-1. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Integral to multi-step synthetic routes for constructing complex molecules with potential therapeutic activity.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays due to its privileged pyrazolopyrimidine structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	5-(4-Ethyl-Phenyl)-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine
CAS No.	676459-69-1
Molecular Formula	C15H16F3N3
Molecular Weight	295.30 g/mol
Synonyms	5-(4-Ethylphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidine; 7-Trifluoromethyl-5-(4-ethylphenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidine; 5-(p-Ethylphenyl)-7-trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine; 676459-69-1; Pyrazolo[1,5-a]pyrimidine, 5-(4-ethylphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Ethyl-Phenyl)-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.