Description

7-Trifluoromethyl-5-Phenyl-4,5,6,7-Tetrahydropyrazo[1,5-A]Pyrimidine CAS NO 676153-52-9 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure incorporating a trifluoromethyl group. This compound is of significant commercial value for its role in streamlining the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Serves as a precursor in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the pyrazolopyrimidine scaffold.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and modulate biological pathways due to its specific structural features.
• Material Science: Investigated as a precursor for specialty chemicals and functional materials where the trifluoromethyl group imparts desirable properties like lipophilicity and stability.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex target molecules.

Basic Information

Product Name	7-Trifluoromethyl-5-Phenyl-4,5,6,7-Tetrahydropyrazo[1,5-A]Pyrimidine
CAS No.	676153-52-9
Molecular Formula	C₁₄H₁₂F₃N₃
Molecular Weight	279.26 g/mol
Synonyms	5-Phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine; 7-(Trifluoromethyl)-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 4,5,6,7-tetrahydro-5-phenyl-7-(trifluoromethyl)-; 676153-52-9; 5-Phenyl-7-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine; 7-Trifluoromethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Trifluoromethyl-5-Phenyl-4,5,6,7-Tetrahydropyrazo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.