Description

1-(4-Fluoro-Benzyl)-3-Nitro-1H-[1,2,4]Triazole is a specialized heterocyclic compound featuring a triazole core substituted with a 4-fluorobenzyl group and a nitro moiety. This unique molecular architecture makes it a valuable building block and intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical synthesis operations seeking to incorporate fluorinated triazole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting infectious diseases or cancer, where the fluorinated triazole scaffold is pharmacologically relevant.
• Agrochemical Research: Used in the development of new fungicides, herbicides, or insecticides, leveraging the bioactivity of the nitro-triazole functional group.
• Chemical Biology & Proteomics: Acts as a reactive handle or a tag in the design of chemical probes for studying enzyme function or protein labeling.
• Material Science Precursor: Can be utilized in the synthesis of specialized ligands for catalysts or in the creation of novel polymers with specific electronic properties.
• Academic & Contract Research: Employed in university and CRO settings for methodological development and exploration of new heterocyclic chemistry.

Basic Information

Product Name	1-(4-Fluoro-Benzyl)-3-Nitro-1H-[1,2,4]Triazole
CAS No.	675130-87-7
Molecular Formula	C9H7FN4O2
Molecular Weight	222.18 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-3-nitro-1H-1,2,4-triazole; 3-Nitro-1-(4-fluorobenzyl)-1H-1,2,4-triazole; 1-(4-Fluorobenzyl)-3-nitro-1,2,4-triazole; 1H-1,2,4-Triazole, 1-[(4-fluorophenyl)methyl]-3-nitro-; 675130-87-7; 4-Fluoro-Benzyl-3-Nitro-Triazole
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluoro-Benzyl)-3-Nitro-1H-[1,2,4]Triazole adheres to stringent in-process controls and final batch release testing. Every lot is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.