Description

5-(5-Acetyl-6-Methyl-2-Oxo-1-(3-(Trifluoromethyl)Phenyl)-1,2,3,4Tetrahydropyrimidin-4-Yl)Picolinonitrile is a high-value, multi-functional heterocyclic compound featuring a tetrahydropyrimidinone core. This molecule is of significant interest for its role as a sophisticated pharmaceutical intermediate and a versatile chemical building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Used in medicinal chemistry and drug discovery programs as a tool compound for target identification and validation due to its complex, drug-like structure.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing complex nitrogen-containing heterocycles for specialty chemical applications.
• Material Science Research: Potential intermediate in the development of advanced organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-(5-Acetyl-6-Methyl-2-Oxo-1-(3-(Trifluoromethyl)Phenyl)-1,2,3,4Tetrahydropyrimidin-4-Yl)Picolinonitrile
CAS No.	675103-35-2
Molecular Formula	C₂₁H₁₅F₃N₄O₂
Molecular Weight	412.37 g/mol
Synonyms	4-(6-Cyanopyridin-3-yl)-5-acetyl-6-methyl-1-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrimidin-2(1H)-one; 5-(5-Acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidin-4-yl)picolinonitrile; 4-(6-Cyano-3-pyridinyl)-5-acetyl-6-methyl-1-[3-(trifluoromethyl)phenyl]-3,4-dihydro-2(1H)-pyrimidinone; 675103-35-2; Tetrahydropyrimidinone-picolinonitrile derivative
EINECS	Contact for details

Quality Control

Our production of 5-(5-Acetyl-6-Methyl-2-Oxo-1-(3-(Trifluoromethyl)Phenyl)-1,2,3,4Tetrahydropyrimidin-4-Yl)Picolinonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.