Description

4-Chloro-2-(5-Chloro-2-Fluorophenyl)-5-Methoxypyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Chemical Research: Serves as a versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science: Potential intermediate in the synthesis of organic electronic materials or liquid crystals due to its rigid, aromatic structure.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.

Basic Information

Product Name	4-Chloro-2-(5-Chloro-2-Fluorophenyl)-5-Methoxypyrimidine
CAS No.	674793-47-6
Molecular Formula	C11H7Cl2FN2O
Molecular Weight	273.09 g/mol
Synonyms	4-Chloro-2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidine; 5-Methoxy-4-chloro-2-(5-chloro-2-fluorophenyl)pyrimidine; 2-(5-Chloro-2-fluorophenyl)-4-chloro-5-methoxypyrimidine; 4-Chloro-2-(5-chloro-2-fluorophenyl)-5-methoxy-pyrimidine; CAS 674793-47-6
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(5-Chloro-2-Fluorophenyl)-5-Methoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.