Description

n-(4,6-Dimethylpyrimidin-2-Yl)-4-(4-Methoxyphenyl) Piperazine-1-Carboximidamide is a high-purity, non-nucleoside pharmaceutical intermediate of significant commercial interest. This compound matters for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific receptor targeting. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug molecules, especially in central nervous system (CNS) and antiviral research.
• Biochemical Research: Used as a reference standard or a ligand in pharmacological studies to investigate receptor binding and enzyme inhibition.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing complex heterocyclic compounds with potential biological activity.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory chemistry and the development of new synthetic methodologies.

Basic Information

Item	Details
Product Name	n-(4,6-Dimethylpyrimidin-2-Yl)-4-(4-Methoxyphenyl) Piperazine-1-Carboximidamide
CAS No.	674363-57-6
Molecular Formula	C18H24N6O
Molecular Weight	340.43 g/mol
Synonyms	4-(4-Methoxyphenyl)-N-(4,6-dimethyl-2-pyrimidinyl)-1-piperazinecarboximidamide; 1-Piperazinecarboximidamide, 4-(4-methoxyphenyl)-N-(4,6-dimethyl-2-pyrimidinyl)-; UNII-8V8K2C3V8W; 674363-57-6; 4-(4-Methoxyphenyl)-N-(4,6-dimethylpyrimidin-2-yl)piperazine-1-carboximidamide; Carboximidamide, N-(4,6-dimethyl-2-pyrimidinyl)-4-(4-methoxyphenyl)-1-piperazine-
EINECS	Contact for details

Quality Control

Our n-(4,6-Dimethylpyrimidin-2-Yl)-4-(4-Methoxyphenyl) Piperazine-1-Carboximidamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.