Description

N⁴-(3,4-Dimethylphenyl)-5-Nitro-N²-(Tetrahydrofuran-2-Ylmethyl)Pyrimidine-2,4,6-Triamine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutic agents. It is primarily needed by R&D laboratories and manufacturing facilities in the pharmaceutical and biotechnology sectors focused on innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Chemical Research & Development: Used as a specialized reagent for constructing complex pyrimidine-based molecular scaffolds in academic and industrial R&D.
• Agrochemical Synthesis: Potential application in the development of new-generation herbicides and fungicides due to its nitro- and amino-substituted pyrimidine core.
• Material Science Research: Investigated for the synthesis of organic ligands and functional materials with specific electronic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	N⁴-(3,4-Dimethylphenyl)-5-Nitro-N²-(Tetrahydrofuran-2-Ylmethyl)Pyrimidine-2,4,6-Triamine
CAS No.	674362-85-7
Molecular Formula	C₁₉H₂₄N₆O₃
Molecular Weight	384.43 g/mol
Synonyms	5-Nitro-N2-[(tetrahydro-2-furanyl)methyl]-N4-(3,4-dimethylphenyl)-2,4,6-pyrimidinetriamine; 2,4,6-Pyrimidinetriamine, N⁴-(3,4-dimethylphenyl)-5-nitro-N²-(tetrahydro-2-furanylmethyl)-; N2-((Tetrahydrofuran-2-yl)methyl)-N4-(3,4-dimethylphenyl)-5-nitropyrimidine-2,4,6-triamine; CAS 674362-85-7; 674362-85-7
EINECS	Contact for details

Quality Control

Our N⁴-(3,4-Dimethylphenyl)-5-Nitro-N²-(Tetrahydrofuran-2-Ylmethyl)Pyrimidine-2,4,6-Triamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with internal quality standards and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.