Description

n-(4-Fluorophenyl)-5-Nitro-2-(Piperidin-1-Yl)Pyrimidine-4,6-Diamine is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine core structure. This compound is critical for research and development in medicinal chemistry, offering a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new molecular entities.
• API Development: A key raw material in the development and scale-up of novel Active Pharmaceutical Ingredients (APIs) with a pyrimidine-diamine scaffold.
• Biochemical Research: Employed as a tool compound in biochemical assays to study protein-ligand interactions and enzyme inhibition.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	n-(4-Fluorophenyl)-5-Nitro-2-(Piperidin-1-Yl)Pyrimidine-4,6-Diamine
CAS No.	674356-50-4
Molecular Formula	C15H17FN6O2
Molecular Weight	332.34 g/mol
Synonyms	4,6-Diamino-5-nitro-2-(1-piperidinyl)-N-(4-fluorophenyl)pyrimidine; 5-Nitro-2-(piperidin-1-yl)-N-(4-fluorophenyl)pyrimidine-4,6-diamine; 2-(Piperidin-1-yl)-5-nitro-N4-(4-fluorophenyl)pyrimidine-4,6-diamine; 674356-50-4; 4-Fluorophenyl-5-nitro-2-piperidin-1-yl-pyrimidine-4,6-diamine; N-(4-Fluorophenyl)-5-nitro-2-(1-piperidinyl)-4,6-pyrimidinediamine
EINECS	Contact for details

Quality Control

Our n-(4-Fluorophenyl)-5-Nitro-2-(Piperidin-1-Yl)Pyrimidine-4,6-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.