Description

3-Bromo-5-Chloropyrazolo[1,5-A]Pyrimidin-7-Amine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of potential kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its pyrazolopyrimidine core.
• Chemical Biology Probe Development: Acts as a precursor for creating tool compounds to study enzyme function and cellular pathways.
• Material Science: Potential building block for organic electronic materials and ligands in catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	3-Bromo-5-Chloropyrazolo[1,5-A]Pyrimidin-7-Amine
CAS No.	674297-88-2
Molecular Formula	C6H4BrClN4
Molecular Weight	247.48 g/mol
Synonyms	7-Amino-3-bromo-5-chloropyrazolo[1,5-a]pyrimidine; 3-Bromo-5-chloro-7-aminopyrazolo[1,5-a]pyrimidine; 3-Bromo-5-chloro-pyrazolo[1,5-a]pyrimidin-7-ylamine; 674297-88-2; 3-Bromo-5-chloro-7H-pyrazolo[1,5-a]pyrimidin-7-amine; Pyrazolo[1,5-a]pyrimidin-7-amine, 3-bromo-5-chloro-; 3-Br-5-Cl-Pyrazolo[1,5-a]pyrimidin-7-amine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloropyrazolo[1,5-A]Pyrimidin-7-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.