Description

N~2~-(Butan-2-Yl)-6-(4-Methylpiperazin-1-Yl)-5-Nitropyrimidine-2,4-Diamine is a specialized pyrimidine derivative, a key chemical intermediate valued for its precise molecular architecture. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel therapeutic agents. It is primarily required by fine chemical manufacturers, pharmaceutical R&D laboratories, and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed as a tool compound or a precursor in biochemical assays to study enzyme interactions and cellular pathways.
• Fine Chemical Synthesis: Acts as a versatile intermediate for the custom synthesis of complex, high-value organic molecules for specialized applications.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis projects and the development of new synthetic methodologies.

Basic Information

Product Name	N~2~-(Butan-2-Yl)-6-(4-Methylpiperazin-1-Yl)-5-Nitropyrimidine-2,4-Diamine
CAS No.	673497-35-3
Molecular Formula	C13H24N8O2
Molecular Weight	324.38 g/mol
Synonyms	2-[(2S)-Butan-2-yl]-6-(4-methylpiperazin-1-yl)-5-nitropyrimidine-2,4-diamine; 6-(4-Methyl-1-piperazinyl)-5-nitro-2-[(1S)-1-methylpropyl]-2,4-pyrimidinediamine; (S)-2-(sec-Butyl)-6-(4-methylpiperazin-1-yl)-5-nitropyrimidine-2,4-diamine; 5-Nitro-6-(4-methylpiperazin-1-yl)-2-(sec-butyl)pyrimidine-2,4-diamine; N2-(sec-Butyl)-6-(4-methylpiperazin-1-yl)-5-nitropyrimidine-2,4-diamine; CAS 673497-35-3
EINECS	Contact for details

Quality Control

Our N~2~-(Butan-2-Yl)-6-(4-Methylpiperazin-1-Yl)-5-Nitropyrimidine-2,4-Diamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.