Description

2-(3,5-Dimethylpiperidin-1-Yl)-n-(4-Fluorophenyl)-5-Nitropyrimidine-4,6-Diamine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex molecules with modified piperidine and pyrimidine scaffolds.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study enzyme interactions and cellular pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	2-(3,5-Dimethylpiperidin-1-Yl)-n-(4-Fluorophenyl)-5-Nitropyrimidine-4,6-Diamine
CAS No.	672340-78-2
Molecular Formula	C17H21FN6O2
Molecular Weight	360.39 g/mol
Synonyms	N-(4-Fluorophenyl)-2-(3,5-dimethyl-1-piperidinyl)-5-nitro-4,6-pyrimidinediamine; 5-Nitro-N4-(4-fluorophenyl)-N2-(3,5-dimethylpiperidin-1-yl)pyrimidine-4,6-diamine; 2-(3,5-Dimethylpiperidin-1-yl)-N-(4-fluorophenyl)-5-nitropyrimidine-4,6-diamine; 672340-78-2; 4,6-Pyrimidinediamine, N-(4-fluorophenyl)-2-(3,5-dimethyl-1-piperidinyl)-5-nitro-
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dimethylpiperidin-1-Yl)-n-(4-Fluorophenyl)-5-Nitropyrimidine-4,6-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure high consistency and reliability for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.