Description

Pyrimidine, 2-[(3R)-3-Methyl-1-Piperazinyl]- (9Ci) is a specialized chiral piperazinyl-substituted pyrimidine derivative, identified by CAS NO 668484-57-9. This compound is a high-value pharmaceutical intermediate and research chemical critical for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing targeted therapies.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Biochemical Tool Compound: Serves as a precursor or reference standard in biochemical assay development and target validation.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its (R)-configured methylpiperazine moiety, enabling the production of enantiomerically pure compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Item	Details
Product Name	Pyrimidine, 2-[(3R)-3-Methyl-1-Piperazinyl]- (9Ci)
CAS No.	668484-57-9
Molecular Formula	C9H14N4
Molecular Weight	178.24 g/mol
Synonyms	2-[(3R)-3-Methylpiperazin-1-yl]pyrimidine; (R)-2-(3-Methylpiperazin-1-yl)pyrimidine; 2-((R)-3-Methyl-1-piperazinyl)pyrimidine; 668484-57-9; UNII-9V6P3I5K6R; 9V6P3I5K6R; AOB67707; BDBM50389385; SCHEMBL21842279; ZINC000006379008
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 2-[(3R)-3-Methyl-1-Piperazinyl]- (9Ci) adheres to stringent quality management systems. Every batch is characterized and tested to ensure identity, purity, and chiral integrity, with analytical methods including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.