Description

Quinazoline, 2-(Chloromethyl)-4-Ethoxy- is a versatile and high-value heterocyclic building block, specifically a substituted quinazoline derivative. This compound is of significant interest in advanced organic synthesis due to its reactive chloromethyl and ethoxy functional groups, which allow for selective modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating specialized ligands, polymers, or organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific quinazoline scaffolds.
• Academic & Institutional Research: Employed in universities and research institutes for methodological development and exploratory chemistry.

Basic Information

Product Name	Quinazoline, 2-(Chloromethyl)-4-Ethoxy-
CAS No.	668276-10-6
Molecular Formula	C11H11ClN2O
Molecular Weight	222.67 g/mol
Synonyms	2-(Chloromethyl)-4-ethoxyquinazoline; 4-ethoxy-2-(chloromethyl)quinazoline; 2-Chloromethyl-4-ethoxyquinazoline; 4-Ethoxy-2-chloromethylquinazoline; Quinazoline, 4-ethoxy-2-(chloromethyl)-; 668276-10-6; 2-(Chloromethyl)-4-ethoxy-quinazoline
EINECS	Contact for details

Quality Control

Every batch of Quinazoline, 2-(Chloromethyl)-4-Ethoxy- is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive research and development applications. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.