Description

2-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzaldehyde is a specialized aromatic aldehyde derivative, distinguished by its trifluoromethyl benzyl ether moiety, which imparts unique electronic and steric properties. This compound serves as a versatile and high-value pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecules for advanced research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorinated aromatic systems into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where fluorinated aromatic units modify electronic properties and solubility.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and fluorescent tags for biochemical and cellular imaging studies.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	2-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzaldehyde
CAS No.	667437-45-8
Molecular Formula	C15H11F3O2
Molecular Weight	280.24 g/mol
Synonyms	2-[(3-(Trifluoromethyl)benzyl)oxy]benzaldehyde; 2-[[[3-(Trifluoromethyl)phenyl]methyl]oxy]benzaldehyde; o-[(3-Trifluoromethylbenzyl)oxy]benzaldehyde; Benzaldehyde, 2-[[[3-(trifluoromethyl)phenyl]methyl]oxy]-; 2-(3-Trifluoromethylbenzyloxy)benzaldehyde; 2-Hydroxybenzaldehyde 3-trifluoromethylbenzyl ether
EINECS	Contact for details

Quality Control

Every batch of 2-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Our standard quality commitment includes HPLC purity ≥98% (typical), with detailed impurity profiling available. A Certificate of Analysis (COA) documenting identity, purity, and relevant physical parameters is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.