Description

1-(4-Methoxyphenyl)-3-(6-{[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Sulfanyl]Methyl}-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Guanidine is a sophisticated heterocyclic organic compound featuring a unique molecular architecture combining guanidine, pyrimidinone, and thiadiazole moieties. This complex structure makes it a valuable advanced pharmaceutical intermediate for research and development in novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of bioactive molecules targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for developing potential inhibitors, particularly in areas like kinase or protease inhibition, due to its guanidine and heterocyclic structure.
• Biochemical Tool Compound: Serves as a research-grade compound for studying biological mechanisms and structure-activity relationships (SAR) in academic and industrial settings.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex, target-specific molecules for pre-clinical evaluation.

Basic Information

Item	Details
Product Name	1-(4-Methoxyphenyl)-3-(6-{[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Sulfanyl]Methyl}-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Guanidine
CAS No.	667431-00-7
Molecular Formula	C₁₆H₁₇N₇O₂S₂
Molecular Weight	403.48 g/mol
Synonyms	2-Guanidino-6-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-4(1H)-pyrimidinone, 4-Methoxyphenyl Derivative; 1-(4-Methoxyphenyl)-3-[6-[[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl]-4-oxo-1,4-dihydropyrimidin-2-yl]guanidine; Guanidine, N-(4-methoxyphenyl)-N'-[6-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-4-oxo-1(4H)-pyrimidinyl]-; CAS 667431-00-7
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR, or MS), and impurity profile is provided with every shipment to support your R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.