Description

Biotinyl-(Glu1)-Gastrin I (Human) Biotinyl-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-Nh2 is a synthetic, biotinylated peptide analog of the human gastrin I hormone, designed for high-affinity detection and isolation applications. This compound is critical for researchers and developers requiring precise, non-radioactive labeling in biochemical assays and diagnostic platforms. It is primarily utilized in pharmaceutical research, proteomics, and the development of advanced in vitro diagnostic (IVD) kits.

Application

• Biomarker Research & Validation: Used as a tagged ligand in studies of gastrin receptor (CCK2R) expression, signaling, and internalization.
• Diagnostic Kit Development: Serves as a key capture or detection reagent in ELISA, lateral flow assays, and other immunoassays targeting gastrin-related peptides.
• Affinity Purification & Pull-Down Assays: Facilitates the isolation and characterization of gastrin-binding proteins and receptor complexes using streptavidin/avidin-based systems.
• Cell Imaging & Microscopy: Enables visualization of receptor localization and trafficking in fixed or live cells when conjugated to fluorescent streptavidin probes.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize novel agonists or antagonists for the gastrin/CCK2 receptor pathway.
• Peptide & Antibody Standard: Acts as a critical reference standard for quality control in the production of gastrin-specific antibodies or calibration of diagnostic assays.

Basic Information

Product Name	Biotinyl-(Glu1)-Gastrin I (Human)
CAS No.	663625-43-2
Molecular Formula	C124H168N28O44S2
Molecular Weight	2795.0 g/mol (theoretical)
Synonyms	Biotinyl-Gastrin I (human); Biotin-Gastrin I; Biotinylated Gastrin I; Gastrin I (1-17), biotinyl-(Glu1)-; Biotinyl-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2; Biotin-Glu1-Gastrin I; Biotin-Labeled Gastrin I Peptide
EINECS	Contact for details

Quality Control

Our Biotinyl-(Glu1)-Gastrin I (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the product desiccated. Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.