Description

n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)-3-(4-Oxoquinazolin-3(4H)-Yl)Propanamide is a sophisticated heterocyclic organic compound that serves as a key building block in advanced pharmaceutical research and development. This molecule is valued for its unique structural features, combining a quinazolinone core with a methyl-thiadiazole moiety, which are pharmacophores of significant interest in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly for applications in oncology and targeted disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition and other enzymatic processes.
• Medicinal Chemistry Research: Used as a core scaffold or a derivatization starting point for structure-activity relationship (SAR) studies in drug discovery programs.
• Oncology Drug Development: Investigated for its potential role in creating compounds with anti-proliferative or apoptotic activity against various cancer cell lines.
• Biochemical Probe Synthesis: Utilized to develop tool compounds for studying specific biological pathways and target validation in vitro.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations that require high-purity, complex intermediates for client-specific synthesis projects.
• Academic Research: Employed in university laboratories for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)-3-(4-Oxoquinazolin-3(4H)-Yl)Propanamide
CAS No.	663200-48-4
Molecular Formula	C₁₅H₁₃N₅O₂S
Molecular Weight	327.36 g/mol
Synonyms	3-(4-Oxo-3,4-dihydroquinazolin-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)propanamide; Propanamide, N-(5-methyl-1,3,4-thiadiazol-2-yl)-3-(4-oxo-3,4-dihydro-2-quinazolinyl)-; 663200-48-4; UNII-9K5J6W3F2I; 9K5J6W3F2I; SCHEMBL218062; BDBM50389385; AKOS025310626
EINECS	Contact for details

Quality Control

Every batch of n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)-3-(4-Oxoquinazolin-3(4H)-Yl)Propanamide is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.