Description

4-Hydroxyquinazoline-8-Carbonitrile is a high-purity, heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its unique quinazoline core functionalized with hydroxy and cyano groups makes it a versatile intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other therapeutic agents targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers and organic electronic materials.
• Chemical Synthesis: A versatile building block for constructing complex heterocyclic frameworks in medicinal and combinatorial chemistry.
• Biochemical Research: Employed as a tool compound or probe in biochemical assays and enzyme inhibition studies.

Basic Information

Product Name	4-Hydroxyquinazoline-8-Carbonitrile
CAS No.	663194-04-5
Molecular Formula	C9H5N3O
Molecular Weight	171.16 g/mol
Synonyms	8-Cyano-4-hydroxyquinazoline; 4-Hydroxy-8-quinazolinecarbonitrile; Quinazoline-8-carbonitrile, 4-hydroxy-; 4(1H)-Quinazolinone-8-carbonitrile; 4-Hydroxyquinazoline-8-carbonitrile; 663194-04-5
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxyquinazoline-8-Carbonitrile is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products meet high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.