Description

4-Amino-5-Bromo-6-Chloropyrimidine is a high-purity halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its multifunctional reactivity, offering distinct sites for nucleophilic substitution and metal-catalyzed cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: A potential monomer or functionalizing agent for creating specialized polymers and electronic materials.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.

Basic Information

Product Name	4-Amino-5-Bromo-6-Chloropyrimidine
CAS No.	663193-80-4
Molecular Formula	C4H3BrClN3
Molecular Weight	208.44 g/mol
Synonyms	5-Bromo-6-chloropyrimidin-4-amine; 4-Amino-5-bromo-6-chloro-pyrimidine; 6-Chloro-5-bromopyrimidin-4-amine; 5-Bromo-6-chloro-4-pyrimidinamine; 4-Pyrimidinamine, 5-bromo-6-chloro-; AB6CP; 5-Bromo-6-chloro-4-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Bromo-6-Chloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.