Description

Pyrido[2,3-D]Pyrimidin-7(8H)-One, 6-Methoxy-8-Methyl-2-(Methylsulfonyl)- is a high-purity heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in medicinal chemistry. Its value lies in its complex pyridopyrimidine scaffold, which is a privileged structure in drug discovery for targeting various kinases and enzymes. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies focused on developing novel therapeutic agents, particularly in oncology and anti-inflammatory drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drugs targeting specific biological pathways.
• Kinase Inhibitor Research: Core scaffold for the development and optimization of potent and selective kinase inhibitors for cancer therapy.
• Medicinal Chemistry & SAR Studies: Used in structure-activity relationship (SAR) explorations to improve drug potency, selectivity, and pharmacokinetic properties.
• Preclinical Drug Development: Serves as a critical material for scale-up synthesis during the preclinical stages of drug development programs.
• Chemical Reference Standard: High-purity material used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in complex multi-step organic syntheses to construct more elaborate molecular architectures.

Basic Information

Item	Details
Product Name	Pyrido[2,3-D]Pyrimidin-7(8H)-One, 6-Methoxy-8-Methyl-2-(Methylsulfonyl)-
CAS No.	661450-74-4
Molecular Formula	C10H11N3O4S
Molecular Weight	269.28 g/mol
Synonyms	6-Methoxy-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one; 2-(Methylsulfonyl)-6-methoxy-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one; 661450-74-4; 6-Methoxy-8-methyl-2-methylsulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-methoxy-8-methyl-2-(methylsulfonyl)-
EINECS	Contact for details

Quality Control

Every batch of Pyrido[2,3-D]Pyrimidin-7(8H)-One, 6-Methoxy-8-Methyl-2-(Methylsulfonyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.