Description

(2-Fluoro-4-Nitrophenyl)Methanol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of a reactive benzylic alcohol group with electron-withdrawing nitro and fluorine substituents, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom can improve lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of novel monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for constructing fluorescent tags or photoaffinity labels for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-directed research and scale-up projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	(2-Fluoro-4-Nitrophenyl)Methanol
CAS No.	660432-43-9
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	2-Fluoro-4-nitrobenzyl alcohol; (2-Fluoro-4-nitrophenyl)methanol; 1-(2-Fluoro-4-nitrophenyl)methanol; α-Fluoro-4-nitrobenzyl alcohol; 2-Fluoro-4-nitrobenzenemethanol; 4-Nitro-2-fluorobenzyl alcohol; Benzenemethanol, 2-fluoro-4-nitro-
EINECS	Contact for details

Quality Control

Every batch of (2-Fluoro-4-Nitrophenyl)Methanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets your specific research or process requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.