Description

Cyclo(L-Alanylglycyl-L-Prolyl-L-Valyl-L-Tyrosyl) is a synthetic cyclic pentapeptide of significant interest in advanced biochemical research and pharmaceutical development. This compound, with CAS number 660397-15-9, is valued for its structural rigidity and potential as a scaffold or bioactive motif. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, drug discovery, and the study of molecular recognition. The cyclic structure offers enhanced metabolic stability compared to linear analogs, making it a crucial tool for investigating novel therapeutic pathways.

Application

• As a reference standard in analytical method development and quality control for peptide-based pharmaceuticals.
• In medicinal chemistry research as a core scaffold for designing novel enzyme inhibitors or receptor modulators.
• For structure-activity relationship (SAR) studies to understand the impact of cyclization on peptide bioactivity and stability.
• As a building block or intermediate in the synthesis of more complex cyclic peptide libraries for high-throughput screening.
• In biophysical studies, such as nuclear magnetic resonance (NMR) spectroscopy, to analyze peptide conformation and dynamics.
• Potential use in the development of diagnostic tools or targeted imaging agents due to its specific molecular recognition properties.

Basic Information

Product Name	Cyclo(L-Alanylglycyl-L-Prolyl-L-Valyl-L-Tyrosyl)
CAS No.	660397-15-9
Molecular Formula	C26H35N5O6
Molecular Weight	513.59 g/mol
Synonyms	Cyclo(Ala-Gly-Pro-Val-Tyr); Cyclo(AGPVY); Cyclic Pentapeptide AGPVY; L-Alanyl-glycyl-L-prolyl-L-valyl-L-tyrosine cyclic peptide; Cyclo(L-Ala-Gly-L-Pro-L-Val-L-Tyr); 660397-15-9; Cyclo(alanine-glycine-proline-valine-tyrosine)
EINECS	Contact for details

Quality Control

Our Cyclo(L-Alanylglycyl-L-Prolyl-L-Valyl-L-Tyrosyl) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.